Bennett C J, Young M N, Darrington H
USC School of Medicine, University of Southern California, Los Angeles, USA.
Paraplegia. 1995 Feb;33(2):69-72. doi: 10.1038/sc.1995.17.
Intermittent catheterization has gained wide acceptance for use in hospitalized patients following spinal cord injury. Most studies evaluating this procedure, however, look only at the infection rate in the male SCI population. In this study the rate and type of infection encountered in the male and female SCI population were evaluated in an inpatient hospital environment. Fifty four patients who were undergoing intermittent catheterization with the MMG/O'Neil catheter system were evaluated. All patients were similar with regard to level of injury and bladder management. There were 45 males and nine females in our study group (n = 45). A total of 10,945 catheterizations were performed with 75 infections indentified. The overall infection rate was 0.68% or one infection for every 146 catheterizations. Of the 45 males there were 58 infections of which 11 (18%) were E. coli. This contrasts with the female population (9) in which there were 17 infections with nine (53%) being E. coli. While a variety of infecting organisms were present in males, females were colonized with either E. coli, enterococcus or Klebsiella. While hospital based intermittent catheterization would appear to be associated with an acceptable low incidence of urinary tract infections (0.68%), infected females have a higher incidence of E. coli (53%) compared to the male population (18%). This study also demonstrated that female patients had a significantly higher infection rate than males (nine females with 17 infections compared to 45 males with 58 infections over the same time period). The higher incidence of urinary tract infections in females with E. coli perhaps is related to the proximity of bowel/stool contamination.
间歇性导尿在脊髓损伤住院患者中已得到广泛应用。然而,大多数评估该操作的研究仅关注男性脊髓损伤人群的感染率。在本研究中,在住院医院环境中评估了男性和女性脊髓损伤人群中感染的发生率和类型。对54例使用MMG/O'Neil导尿系统进行间歇性导尿的患者进行了评估。所有患者在损伤水平和膀胱管理方面相似。我们的研究组中有45名男性和9名女性(n = 45)。共进行了10945次导尿,发现75例感染。总体感染率为0.68%,即每146次导尿中有1例感染。在45名男性中,有58例感染,其中11例(18%)为大肠杆菌感染。相比之下,女性人群(9例感染)中有17例感染,其中9例(53%)为大肠杆菌感染。虽然男性中存在多种感染病原体,但女性主要被大肠杆菌、肠球菌或克雷伯菌定植。虽然基于医院的间歇性导尿似乎与可接受的低尿路感染发生率(0.68%)相关,但感染的女性中大肠杆菌感染的发生率(53%)高于男性人群(18%)。本研究还表明,女性患者的感染率明显高于男性(在同一时间段内,9名女性有17例感染,而45名男性有58例感染)。女性大肠杆菌引起的尿路感染发生率较高可能与肠道/粪便污染的接近程度有关。