[持续气道正压通气和双水平气道正压通气对阻塞性睡眠呼吸暂停综合征患者每搏输出量的影响]
[Effect of CPAP and BIPAP on stroke volume in patients with obstructive sleep apnea syndrome].
作者信息
Weber U, Kellner C, Burbach R, Kirchheiner T, Rühle K H
机构信息
Klinik Ambrock, Zentrum für Pneumologie, Hagen.
出版信息
Pneumologie. 1995 Mar;49(3):233-5.
We studied the effect of CPAP and BIPAP on cardiac output (CO) in 23 male obstructive sleep apnea (OSAS) patients with cardiac history but without congestive heart failure (CHF) during wakefulness using the thermodilution method. CPAP was applied at 10 cm H2O and 15 cm H2O, BIPAP at 10/0 cm H2O and 15/10 cm H2O. CO only decreased significantly by 14.6 +/- 11.8% at 15 cm H2O CPAP and by 13.4 +/- 10.0% at 15/10 cm H2O BIPAP. CPAP and BIPAP did not differ in altering hemodynamics. So sleep apnea patients without CHF develop no severe decrease of CO during nasal positive pressure ventilation up to 15 cm 2O.
我们采用热稀释法研究了持续气道正压通气（CPAP）和双水平气道正压通气（BIPAP）对23例有心脏病史但无充血性心力衰竭（CHF）的男性阻塞性睡眠呼吸暂停（OSAS）患者清醒状态下心输出量（CO）的影响。CPAP分别设置为10厘米水柱和15厘米水柱，BIPAP分别设置为10/0厘米水柱和15/10厘米水柱。仅在15厘米水柱CPAP时CO显著下降14.6±11.8%，在15/10厘米水柱BIPAP时CO显著下降13.4±10.0%。CPAP和BIPAP在改变血流动力学方面无差异。因此，无CHF的睡眠呼吸暂停患者在高达15厘米水柱的鼻正压通气期间不会出现CO的严重下降。
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