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[夏科,疾病的发现者]

[Charcot, discoverer of diseases].

作者信息

Lellouch A

机构信息

Centre Hospitalier de Saint-Germain-en-Laye, Département d'Information Médicale, St-Germain-en-Laye.

出版信息

Rev Neurol (Paris). 1994 Aug-Sep;150(8-9):506-10.

PMID:7754284
Abstract

Nowadays, one hundred years following Charcot's death (1893), neurologists remember his original contributions in the field of neurological disorders. The aim of this work is to assess the extraordinary Charcot's ability to create new diseases outside the field of neurology, mainly in internal medicine and in geriatric disorders. A good way to evaluate his abilities is to compare the state of medical knowledge before and after Charcot. Before, "chronic rheumatic disease" was not distinguished from gout and shaking falsy was confused with other tremors occurring in the elderly. Among vascular cerebral diseases ("apoplexy"), physicians could not recognize those following a bleeding process from those induced by an ischaemic brain disease. After Charcot's papers, these various disorders were better known and well defined from their pathology, aetiology and mechanisms. According to his obsessive personality, Charcot liked classifying and labeling diseases. Some nosographic frameworks were nevertheless inappropriate. Thus, in the field of joint disorders, Charcot included in the same pathological entity ("chronic rheumatic disease") various arthropathies such as rheumatic arthritis and osteo-arthritis. In France, this mistake hindered the understanding of the mechanism of these diseases. Though Charcot made mistakes when he described new pathological disorders, these mistakes were of little consequence, compared to the importance of his main nosologic contributions. As a whole, Charcot's scientific methodology seemed to be accurate and successful.

摘要

如今,在夏科(Charcot)逝世(1893年)一百年后,神经科医生铭记着他在神经系统疾病领域的开创性贡献。本文旨在评估夏科在神经学领域之外创造新疾病的非凡能力,主要涉及内科医学和老年疾病。评估他能力的一个好方法是比较夏科前后医学知识的状况。此前,“慢性风湿性疾病”与痛风未作区分,震颤谵妄与老年人出现的其他震颤相混淆。在脑血管疾病(“中风”)中,医生无法区分出血性疾病与缺血性脑疾病引发的疾病。在夏科发表论文之后,这些不同的疾病从病理学、病因学和发病机制方面得到了更好的了解和明确界定。出于其偏执的性格,夏科喜欢对疾病进行分类和命名。然而,有些疾病分类框架并不恰当。因此,在关节疾病领域,夏科将各种关节病,如风湿性关节炎和骨关节炎,归入同一个病理实体(“慢性风湿性疾病”)。在法国,这一错误阻碍了对这些疾病发病机制的理解。尽管夏科在描述新的病理疾病时犯了错误,但与他主要的疾病分类学贡献相比,这些错误微不足道。总体而言,夏科的科学方法似乎准确且成功。

相似文献

1
[Charcot, discoverer of diseases].[夏科,疾病的发现者]
Rev Neurol (Paris). 1994 Aug-Sep;150(8-9):506-10.
2
Charcot and Brazil.夏科和巴西。
Arq Neuropsiquiatr. 2001 Jun;59(2-A):295-9. doi: 10.1590/s0004-282x2001000200032.
3
[Edouard Brissaud (1852-1909), Charcot's favorite pupil].[爱德华·布里索(1852 - 1909),夏科最喜欢的学生]
Hist Sci Med. 2010 Jul-Sep;44(3):247-55.
4
"Stat Rosa Pristina Nomine, Nomina Nuda Tenemus": The Many Syndromes, Diseases, and Anatomic Structures Bearing Jean-Martin Charcot's Name.“白玫瑰以之名,我们拥有赤裸之名”:以让-马丁·夏科命名的多种综合征、疾病和解剖结构。
Eur Neurol. 2020;83(5):550-553. doi: 10.1159/000511028. Epub 2020 Oct 5.
5
Charcot's skepticism.夏科的怀疑态度。
Arq Neuropsiquiatr. 2012 Nov;70(11):897-9. doi: 10.1590/s0004-282x2012001100014.
6
Chapter 15: Jean-Martin Charcot and the anatomo-clinical method of neurology.第15章:让-马丁·沙可与神经病学的解剖临床方法
Handb Clin Neurol. 2010;95:203-12. doi: 10.1016/S0072-9752(08)02115-5.
7
Jean-Martin Charcot: neurologist by avocation, nephrologist by yearning.让-马丁·沙可:神经科医生是他的业余爱好,肾病学家是他的向往。
J Nephrol. 2011 May-Jun;24 Suppl 17:S4-11. doi: 10.5301/JN.2011.6453.
8
The prefaces by Charcot: leitmotifs of an international career.夏科的序言:一段国际职业生涯的主旨
Neurology. 2003 Apr 22;60(8):1333-40. doi: 10.1212/01.wnl.0000055925.50060.64.
9
[Osteoarticular diseases from J.M. Charcot to the present time].[从J.M.夏科时代至今的骨关节疾病]
Rev Neurol (Paris). 1982;138(12):997-1008.
10
[Creation of Charcot's chair].[夏科氏椅的制作]
Rev Neurol (Paris). 1982;138(12):887-92.

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How great was the influence of his origins and descendants on Charcot's behaviors?他的出身和后代对夏科的行为有多大影响?
Arq Neuropsiquiatr. 2025 Mar;83(3):1-4. doi: 10.1055/s-0045-1806921. Epub 2025 May 9.
2
Jean-Martin Charcot: the polymath.让-马丁·沙可:博学者。
Arq Neuropsiquiatr. 2023 Dec;81(12):1098-1111. doi: 10.1055/s-0043-1775984. Epub 2023 Oct 29.