Gray J A
Department of Psychology, Institute of Psychiatry, London, UK.
Rev Neurol (Paris). 1994 Aug-Sep;150(8-9):605-13.
The paper presents a model of the behavioural functions and information processing discharged jointly by the limbic system (especially, the hippocampal formation and amygdala) and the basal ganglia (both the dorsal and ventral striatal systems). In general terms, the limbic system plus basal ganglia act as a mechanism for the attainment of goals. The sensory aspects of this overall goal-direction function (recognition of goals and evaluation of the outcomes of action) are dealt with in the limbic system; the motor aspects (establishment and execution of motor programs), in the basal ganglia. The model is applied to an understanding of the neuropsychology of schizophrenia (in particular, positive psychotic symptoms) and obsessive-compulsive disorder. In both cases, emphasis is placed on the interaction between the limbic system and the basal ganglia.
本文提出了一种由边缘系统（特别是海马结构和杏仁核）和基底神经节（背侧和腹侧纹状体系统）共同执行的行为功能和信息处理模型。一般来说，边缘系统加上基底神经节充当实现目标的一种机制。这种整体目标导向功能的感觉方面（目标识别和行动结果评估）由边缘系统处理；运动方面（运动程序的建立和执行）由基底神经节处理。该模型被应用于理解精神分裂症（特别是阳性精神病性症状）和强迫症的神经心理学。在这两种情况下，重点都放在边缘系统和基底神经节之间的相互作用上。
