Bermúdez-de Rocha M V, Lozano-Meléndez F E, Tamez-Rodríguez V A, Díaz-Cuello G, Piñeyro-López A
Departamento de Farmacología y Toxicología, Facultad de Medicina, Universidad Autónoma de Nuevo León (FM, UANL), México.
Salud Publica Mex. 1995 Jan-Feb;37(1):57-62.
Intoxication produced by Karwinskia humboldtiana presents a neurological picture similar to that of poliomyelitis, Guillain-Barré syndrome or other polyradiculoneuritis with which it is frequently confused. The purpose of this paper is to report the frequency of this intoxication, by means of the antecedent of ingestion of the fruit and the detection of toxins in blood using a thin layer chromatography method. One hundred fifty four samples of cases with acute flaccid paralysis from 18 states of the country were received. The antecedent of ingestion in 56 of them was corroborated and the detection was positive in 50 of these. In 98 patients there was not antecedent of ingestion and detection was negative in 95 of them. We estimated that the sensibility and specificity of detection method are 89% and 96.9% respectively.
由洪堡卡罗琳玉蕊果实中毒所引发的症状呈现出与小儿麻痹症、格林-巴利综合征或其他多发性神经根神经炎相似的神经学症状，常常容易混淆。本文旨在通过食用该果实的病史以及运用薄层色谱法检测血液中的毒素，来报告这种中毒情况的发生率。我们收到了来自该国18个州的154例急性弛缓性麻痹病例样本。其中56例证实有食用史，且其中50例检测呈阳性。98例患者无食用史，其中95例检测呈阴性。我们估计该检测方法的灵敏度和特异性分别为89%和96.9%。
