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[洪堡卡罗琳草导致的家族性中毒]

[Familial poisoning with Karwinskia humboldtiana].

作者信息

Bermúdez de Rocha M V, Lozano Meléndez F E, Salazar Leal M E, Waksman de Torres N, Piñeyro López A

机构信息

Departamento de Farmacología y Toxicología, Fac. de Medicina de la U.A.N.L., Monterrey, Nuevo León, México.

出版信息

Gac Med Mex. 1995 Jan-Feb;131(1):100-6.

PMID:7493727
Abstract

The ingestion of ripe fruit of the Karwinskia humboldtiana, a shrub commonly known as tullidora or coyotillo, produces an intoxication described in the literature as a symmetric flaccid paralysis of the hind limbs, progressive and ascendent, that in severe cases may cause bulbar paralysis and death. The cause of an acute accidental intoxication of an entire family is presented here, wherein ten out of thirteen members ingested the ripe fruit of the tullidora. Three died, the father and two daughters. For the first time the toxins determination in blood by thin layer chromatography method is described. This method supports the diagnosis with other polyradiculoneuritis such as poliomyelitis and the Guillain Barre's syndrome.

摘要

摄入一种俗称图利多拉或小狼刺的灌木——洪堡氏卡氏木的成熟果实,会导致一种文献中描述为后肢对称性弛缓性麻痹、呈进行性且上行性的中毒症状,在严重情况下可能导致延髓麻痹和死亡。本文介绍了一个全家急性意外中毒的案例,其中13名家庭成员中有10人摄入了图利多拉的成熟果实。三人死亡,分别是父亲和两个女儿。本文首次描述了用薄层色谱法测定血液中的毒素。该方法有助于与其他多神经根神经炎(如小儿麻痹症和格林-巴利综合征)进行鉴别诊断。

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