[The effect of the transmembrane potential level on the dynamic extinction of the amplitude of the synaptic reactions in the snail under potential-fixation conditions].

The goal of this work was to describe a contribution of postsynaptic membrane in synaptic plasticity. To solve this problem the influence of the level of transmembrane potential on the dynamics of transmembrane synaptic current amplitude was studied during rhythmical stimulation of the nerve. It was shown that with increase of transmembrane potential value the slope of the function of transmembrane current decrease became steeper. It was also shown that with higher stimulation frequency the influence of transmembrane holding potential upon the dynamics of synaptic reaction increased. The data obtained can be considered as an evidence to the contribution of postsynaptic membrane in synaptic plasticity.