Kol S, Thaler I, Paz N, Shmueli O
Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.
Am J Obstet Gynecol. 1995 May;172(5):1372-9. doi: 10.1016/0002-9378(95)90465-4.
Our purpose was to evaluate an artificial neural network in the interpretation of nonstress tests.
A nonlinear artificial neural network trained by backpropagation was taught to interpret records of nonstress tests by two learning sets. The first set contained nonstress tests that were similarly interpreted by three human experts; the second set contained a subset of nonstress tests that led to interobserver disagreement. Both "raw" fetal heart rate and uterine contraction data and 17 quantified variables obtained by automated computer analysis were introduced to the input layer. After training, the network was tested by presenting it with input patterns to which it had not been exposed. The performance of the system was examined in relation to the human expert.
After training the neural network with the first set, a sensitivity of 88.9% and a false-positive rate of 4.3% were obtained at testing. When the learning and test set contained records that led to interobserver disagreement, a sensitivity of 86.7% and a false-positive rate of 19.7% were obtained. Sixty percent of fetal heart rate records interpreted as abnormal by the neural network were interpreted likewise by the human experts.
The results obtained are encouraging in that the neural network could discriminate between normal and abnormal nonstress tests. Further evaluation of this new technique is mandatory to evaluate its efficacy and reliability in interpreting fetal heart rate records.
我们的目的是评估人工神经网络在无应激试验解读中的作用。
通过反向传播训练的非线性人工神经网络被教导通过两个学习集来解读无应激试验记录。第一组包含三位人类专家给出相似解读的无应激试验;第二组包含导致观察者间意见不一致的无应激试验子集。“原始”胎儿心率和宫缩数据以及通过自动计算机分析获得的17个量化变量被引入输入层。训练后,通过向网络呈现其未接触过的输入模式对网络进行测试。该系统的性能与人类专家的性能进行了比较。
用第一组对神经网络进行训练后,测试时获得了88.9%的灵敏度和4.3%的假阳性率。当学习集和测试集包含导致观察者间意见不一致的记录时,获得了86.7%的灵敏度和19.7%的假阳性率。神经网络解读为异常的胎儿心率记录中有60%被人类专家同样解读为异常。
所获得的结果令人鼓舞,因为神经网络能够区分正常和异常的无应激试验。必须对这项新技术进行进一步评估,以评估其在解读胎儿心率记录方面的有效性和可靠性。