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Soc Sci Med. 1994 Jun;38(11):1509-19. doi: 10.1016/0277-9536(94)90113-9.
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Chronic non-specific lung disease and occupational exposures estimated by means of a job exposure matrix: the Zutphen Study.通过工作暴露矩阵估算慢性非特异性肺部疾病与职业暴露:祖特芬研究
Int J Epidemiol. 1989 Jun;18(2):382-9. doi: 10.1093/ije/18.2.382.
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Occupational exposure and 25-year incidence rate of non-specific lung disease: the Zutphen Study.
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工作特征和生活方式作为老年市政雇员慢性非特异性肺病发病的预测因素

Work characteristics and lifestyle as predictors in the development of chronic non-specific lung disease among elderly municipal employees.

作者信息

Tammilehto L, Tuomi K

机构信息

Finnish Institute of Occupational Health, Department of Epidemiology and Biostatistics, Helsinki.

出版信息

Occup Environ Med. 1995 Feb;52(2):134-7. doi: 10.1136/oem.52.2.134.

DOI:10.1136/oem.52.2.134
PMID:7757167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1128168/
Abstract

OBJECTIVES

This study prospectively evaluated factors of working conditions and lifestyle in the development of chronic non-specific lung disease (CNSLD).

METHODS

Baseline data were collected in 1981 from 5386 municipal employees born in 1923-35 who had no diagnosed CNSLD. The subjects were studied again in 1985 with a postal questionnaire. The predictors of CNSLD were selected by multivariate logistic regression analysis.

RESULTS

159 (3%) reported the development of CNSLD confirmed by a physician. During the 4.6 year follow up period the average annual incidence was 6.5/1000 subjects. In men the logit model followed was: smoking (odds ratio (OR) 1.17, 95% confidence interval (95% CI) 1.06-1.29), tight work schedule (OR 1.31, 95% CI 1.03-1.65), loss of a close friend (OR 2.21, 95% CI 1.13-4.31), and retirement of a spouse (OR 3.31, 95% CI 1.35-8.11). In women the selected risk factors were: smoking (OR 1.22, 95% CI 1.01-1.38), atopy (OR 1.99, 95% CI 1.12-3.53), physically heavy work (OR 1.65, 95% CI 1.09-2.29), poor physical working conditions such as heat, cold, changing temperature (OR 1.41, 95% CI 1.13-1.75), and infrequent communication with other people at work (OR 1.25, 95% CI 1.05-1.49).

CONCLUSION

The differences in the predictors of the incidence of CNSLD between men and women were partly explained by different smoking habits, frequency of atopy, and working conditions. In men the significance of life events (loss of close friend and retirement of wife) need further investigation.

摘要

目的

本研究前瞻性评估了慢性非特异性肺病(CNSLD)发生过程中的工作条件和生活方式因素。

方法

1981年收集了5386名出生于1923年至1935年且未被诊断患有CNSLD的市政雇员的基线数据。1985年通过邮寄问卷对这些受试者再次进行研究。通过多因素逻辑回归分析选择CNSLD的预测因素。

结果

159人(3%)报告经医生确诊患有CNSLD。在4.6年的随访期内,年平均发病率为6.5/1000名受试者。在男性中,遵循的逻辑模型为:吸烟(比值比(OR)1.17,95%置信区间(95%CI)1.06 - 1.29)、工作时间表紧张(OR 1.31,95%CI 1.03 - 1.65)、失去亲密朋友(OR 2.21,95%CI 1.13 - 4.31)以及配偶退休(OR 3.31,95%CI 1.35 - 8.11)。在女性中,选定的风险因素为:吸烟(OR 1.22,95%CI 1.01 - 1.38)、特应性(OR 1.99,95%CI 1.12 - 3.53)、体力繁重工作(OR 1.65,95%CI 1.09 - 2.29)、诸如炎热、寒冷、温度变化等恶劣的身体工作条件(OR 1.41,95%CI 1.13 - 1.75)以及工作中与他人交流不频繁(OR 1.25,95%CI 1.05 - 1.49)。

结论

男性和女性CNSLD发病率预测因素的差异部分可由不同的吸烟习惯、特应性频率和工作条件来解释。男性中生活事件(失去亲密朋友和妻子退休)的重要性需要进一步研究。