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[编码抗生素耐药性的基因分布流行病学]

[Epidemiology of the distribution of genes coding for resistance to antibiotics].

作者信息

Kallová J, Kettner M

机构信息

Katedra mikrobiológie a virológie, Prírodovedecká fakulta Univerzity Komenského, Bratislava.

出版信息

Epidemiol Mikrobiol Imunol. 1995 Mar;44(1):20-5.

PMID:7757344
Abstract

The increasing prevalence of isolated bacteria resistant to antibiotics is one of the serious problems of contemporary clinical medicine because it is the main cause of failing treatment of infectious diseases. Therefore great efforts are made to reveal the mechanisms of resistance to antibiotics and to elucidate their epidemiology. In the submitted paper the author summarizes the present stage of knowledge concerning mechanisms of resistance to antibiotics and mechanisms of their distribution in nature. In the conclusion the authors draw attention to the important character of transmitted resistance to antibiotics from the aspect of its rapid spread among the microbial population.

摘要

对抗生素耐药的孤立细菌日益普遍,这是当代临床医学面临的严重问题之一,因为它是传染病治疗失败的主要原因。因此,人们付出了巨大努力来揭示抗生素耐药机制并阐明其流行病学特征。在提交的论文中,作者总结了目前关于抗生素耐药机制及其在自然界中传播机制的知识阶段。在结论中,作者从抗生素耐药性在微生物群体中迅速传播的角度提请人们注意其传播抗性的重要特征。

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