Multiple metastases of mammary carcinoma cell lines isolated from feral mouse.

Two established cell lines (JYG-A and B) isolated from mammary carcinoma tissues of M. m. musculus Sub-Jyg (a chinese wild mouse) showed multiple metastasis in the lung (100%), liver (40-60%), kidney (40-80%), lymph node (20-60%) and other organs of the nude mice inoculated with these cells subcutaneously or intravenously. In addition, 100% brain metastasis or infiltration was observed only when inoculated with JYG-B cells intravenously.