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肾移植后脂质代谢紊乱(作者译)

[Disturbances of lipid metabolism following renal transplantation (author's transl)].

作者信息

Zazgornik J, Bayer P M, Schmidt P, Pils P, Bratusch-Marrain P, Kopsa H

出版信息

Wien Klin Wochenschr. 1975 Oct 17;87(19):648-50.

PMID:775798
Abstract

The serum cholesterol and triglyceride levels and the lipoprotein electrophoretic pattern were investigated in 33 kidney transplant recipients. These patients showed elevated serum cholesterol and triglyceride levels in comparison with a group of healthy control subjects. Lipoprotein electrophoresis showed a predomination of types II a, II b and IV, according to Frederickson. The causes of the disturbances in lipid metabolism are discussed. There is a definite risk of cardiovascular disease in kidney transplant patients as a consequence of the altered lipid metabolism.

摘要

对33名肾移植受者的血清胆固醇、甘油三酯水平及脂蛋白电泳图谱进行了研究。与一组健康对照者相比,这些患者的血清胆固醇和甘油三酯水平升高。根据弗雷德里克森的分类,脂蛋白电泳显示以Ⅱa型、Ⅱb型和Ⅳ型为主。文中讨论了脂质代谢紊乱的原因。肾移植患者由于脂质代谢改变存在明确的心血管疾病风险。

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