[慢性血液透析患者及肾移植后重要血清脂质组分的行为]

[Behavior of important serum lipid fractions in chronic hemodialysis patients and following kidney transplantation].

作者信息

Luci V, Wichmann T, Giesselmann M, Koall W, Mampel E

出版信息

Z Gesamte Inn Med. 1983 Mar 1;38(5):153-7.

Abstract

In patients in the chronic programme of haemodialysis and 51 patients with transplanted kidney selected lipid-chemical parameters were investigated and compared. 1. Disturbances of the lipid metabolism more frequently occurred in patients with transplanted kidney than in chronically haemodialyzed patients. 2. Triglycerides, total cholesterol and LDL cholesterol were more frequently increased in patients with transplanted kidney than in chronically haemodialysed patients. 3. The HDL cholesterol of patients with transplanted kidney was only somewhat higher in comparison to patients in the chronic haemodialysis programme. 4. Sex-specific differences of the HDL cholesterol level were neither in chronically haemodialysed patients nor in patients with transplanted kidney. 5. Klimov-index and LDL/HDL cholesterol quotient referred to a permanently high risk of cardiovascular complications even after transplantation of a kidney.

摘要

对慢性血液透析项目中的患者以及51例肾移植患者的血脂化学参数进行了调查和比较。1. 肾移植患者比慢性血液透析患者更频繁地出现脂质代谢紊乱。2. 肾移植患者的甘油三酯、总胆固醇和低密度脂蛋白胆固醇比慢性血液透析患者更频繁地升高。3. 与慢性血液透析项目中的患者相比，肾移植患者的高密度脂蛋白胆固醇仅略高。4. 慢性血液透析患者和肾移植患者的高密度脂蛋白胆固醇水平均无性别差异。5. 即使在肾移植后，克里莫夫指数和低密度脂蛋白/高密度脂蛋白胆固醇比值也表明心血管并发症的风险持续很高。