Lysaker P H, Bell M D, Bioty S M, Zito W S
Veterans Administration Medical Center, West Haven, CT 06516, USA.
Compr Psychiatry. 1995 Mar-Apr;36(2):113-7. doi: 10.1016/s0010-440x(95)90105-1.
Weekly assessments of depression, anxiety, and positive and negative symptoms were performed on 80 subjects with schizophrenia or schizoaffective disorder. Using procedures previously reported in another study, the frequency of significant correlations between the sum of anxiety and depression ratings and positive symptoms was compared with the frequency of significant correlations between the sum of anxiety and depression ratings and negative symptoms. Results confirm that dysphoria in schizophrenia tends to be more frequently associated with positive versus negative symptoms, regardless of diagnostic subtype or symptom type. This provides further evidence of the independence of negative symptoms from dysphoria and suggests that the level of positive symptoms and level of dysphoria may mutually influence one another.
对80名精神分裂症或分裂情感性障碍患者进行了抑郁、焦虑以及阳性和阴性症状的每周评估。采用另一项研究中先前报告的程序，将焦虑和抑郁评分总和与阳性症状之间显著相关性的频率，与焦虑和抑郁评分总和与阴性症状之间显著相关性的频率进行比较。结果证实，无论诊断亚型或症状类型如何，精神分裂症中的烦躁不安往往更常与阳性症状而非阴性症状相关。这进一步证明了阴性症状与烦躁不安的独立性，并表明阳性症状水平和烦躁不安水平可能相互影响。
