Graham S L, Drance S M
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Graefes Arch Clin Exp Ophthalmol. 1995 Mar;233(3):140-9. doi: 10.1007/BF00166606.
The interpretation of high-pass resolution perimetry (HRP) fields can be difficult. An age-related probability plot was derived from a known data base to determine whether this improved specificity and sensitivity in early glaucoma detection.
Forty glaucoma patients with minor field loss and 40 normals of equivalent age and sex underwent HRP. All had previous Humphrey field data available for comparison. The detection of previously confirmed field defects by HRP was examined using different parameters.
Using the age-corrected 95% confidence levels gave the best results, with sensitivity of 82.5% (33/40) and specificity of 85% (34/40). Using the contour plot yielded lower sensitivity (67.5%), while subjectively "eyeballing" the ring printout gave higher sensitivity (90%), but led to poor specificity (72.5%).
The use of a probability plot enhances the performance of HRP. A certain proportion of cases may be missed using one criterion alone, but combining the information with other indices can increase the yield.
高通分辨视野计（HRP）视野结果的解读可能存在困难。从一个已知数据库得出了与年龄相关的概率图，以确定其是否能提高早期青光眼检测的特异性和敏感性。
40例有轻微视野缺损的青光眼患者和40例年龄及性别匹配的正常人接受了HRP检查。所有人之前均有Humphrey视野数据可供比较。使用不同参数检查HRP对先前已确诊视野缺损的检测情况。
采用年龄校正后的95%置信水平得出的结果最佳，敏感性为82.5%（33/40），特异性为85%（34/40）。使用等高线图得出的敏感性较低（67.5%），而主观“目测”环形打印结果得出的敏感性较高（90%），但特异性较差（72.5%）。
使用概率图可提高HRP的性能。单独使用一种标准可能会遗漏一定比例的病例，但将该信息与其他指标相结合可提高检出率。
