Kelner G S, Zlotnik A
DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304, USA.
J Leukoc Biol. 1995 May;57(5):778-81. doi: 10.1002/jlb.57.5.778.
By using a variety of molecular techniques, we have characterized the cytokine profile of pro-T cells. During this characterization we cloned a novel cytokine that has chemotactic activities. We have designated this cytokine lymphotactin. The structural analysis, chromosomal location, and biological properties of lymphotactin provide strong evidence that this cytokine represents a new class of chemokine.
通过使用多种分子技术，我们已经对前T细胞的细胞因子谱进行了表征。在这个表征过程中，我们克隆了一种具有趋化活性的新型细胞因子。我们将这种细胞因子命名为淋巴细胞趋化因子。淋巴细胞趋化因子的结构分析、染色体定位和生物学特性提供了有力证据，表明这种细胞因子代表了一类新的趋化因子。
