Fung Y K, Meade A G, Rack E P, Blotcky A J, Claassen J P, Beatty M W, Durham T
Department of Oral Biology, University of Nebraska Medical Center, College of Dentistry, Lincoln 68583-0740, USA.
J Toxicol Clin Toxicol. 1995;33(3):243-7. doi: 10.3109/15563659509017991.
Trace element neurotoxicity can be an etiologic factor for Alzheimer's disease. This cross sectional clinical study determined blood mercury in patients with diagnosed Alzheimer's disease as compared to control subjects without known central nervous system and renal disorders. Unique within the confines of a nursing home, all subjects were exposed to the same environment and consumed a diet without fish and seafood for a period of three months prior to the study. The results of this study show that blood mercury concentrations detected in subjects with Alzheimer's disease were not statistically different than that of control subjects. Ratios of blood mercury to blood selenium were also determined and no statistical difference was found between these two groups.
微量元素神经毒性可能是阿尔茨海默病的一个病因。这项横断面临床研究测定了已确诊的阿尔茨海默病患者与无已知中枢神经系统和肾脏疾病的对照受试者的血汞水平。在养老院范围内独一无二的是，所有受试者都暴露于相同环境中，并且在研究前三个月食用不含鱼类和海鲜的饮食。这项研究结果表明，阿尔茨海默病患者检测到的血汞浓度与对照受试者相比无统计学差异。还测定了血汞与血硒的比值，两组之间未发现统计学差异。
