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Mechanisms for the pleiotropic effects of the agouti gene.

作者信息

Manne J, Argeson A C, Siracusa L D

机构信息

Jefferson Cancer Institute, Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, PA 19107, USA.

出版信息

Proc Natl Acad Sci U S A. 1995 May 23;92(11):4721-4. doi: 10.1073/pnas.92.11.4721.

DOI:10.1073/pnas.92.11.4721
PMID:7761389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC41778/
Abstract
摘要

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Mechanisms for the pleiotropic effects of the agouti gene.刺鼠基因多效性效应的机制。
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2
Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.小鼠刺鼠基因的克隆表明，在携带致死性黄色突变的小鼠中普遍表达一种分泌蛋白。
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4
A transgenic mouse assay for agouti protein activity.一种用于检测刺豚鼠蛋白活性的转基因小鼠试验。
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5
The molecular basis for dominant yellow agouti coat color mutations.显性黄色刺鼠毛色突变的分子基础。
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本文引用的文献

1
More to colour than meets the eye.色彩之中别有洞天。
Curr Biol. 1993 Aug 1;3(8):518-21. doi: 10.1016/0960-9822(93)90045-p.
2
Ionic basis of hypertension, insulin resistance, vascular disease, and related disorders. The mechanism of "syndrome X".
Am J Hypertens. 1993 Apr;6(4):123S-134S. doi: 10.1093/ajh/6.4s.123s.
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Cytosolic calcium and insulin resistance.胞质钙与胰岛素抵抗
Am J Kidney Dis. 1993 Jun;21(6 Suppl 3):32-8. doi: 10.1016/0272-6386(93)70122-f.
4
Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.小鼠刺鼠基因的克隆表明，在携带致死性黄色突变的小鼠中普遍表达一种分泌蛋白。
Genes Dev. 1993 Mar;7(3):454-67. doi: 10.1101/gad.7.3.454.
5
New roles for G-protein beta gamma-dimers in transmembrane signalling.G蛋白βγ二聚体在跨膜信号传导中的新作用。
Nature. 1993 Sep 30;365(6445):403-6. doi: 10.1038/365403a0.
6
Inositol trisphosphate and calcium signalling.肌醇三磷酸与钙信号传导
Nature. 1993 Jan 28;361(6410):315-25. doi: 10.1038/361315a0.
7
The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein.纯合致死性黄色小鼠（Ay/Ay）的胚胎致死性与一种新型RNA结合蛋白的破坏有关。
Genes Dev. 1993 Jul;7(7A):1203-13. doi: 10.1101/gad.7.7a.1203.
8
Evidence of mammalian Ca2+ channel inhibitors in venom of the spider Plectreurys tristis.
Toxicon. 1993 Oct;31(10):1249-56. doi: 10.1016/0041-0101(93)90398-3.
9
Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene.背部和腹部色素沉着的差异是由小鼠刺鼠基因的区域表达引起的。
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5667-71. doi: 10.1073/pnas.91.12.5667.
10
Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene.黄色A(vy)/-小鼠中的肥胖、糖尿病和肿瘤形成：刺鼠基因的异位表达
FASEB J. 1994 May;8(8):479-88. doi: 10.1096/fasebj.8.8.8181666.