Tebala G D, Ceriati F, Miani N, Nori S, Piantelli M, Ceriati E, Cotroneo A
Department of Surgery, University of the Sacred Heart, Rome, Italy.
Riv Eur Sci Med Farmacol. 1994 Jan-Apr;16(1-2):13-20.
Authors reports the results of an experimental study on the usefulness of n-butyl-2-cyanoacrylate in abdominal surgery. The research, performed on Wistar rats and Landrace pigs, is constituted by an early phase, to verify the tissue reaction to the n-butyl-2-cyano-acrylate and its adhesive properties, and a main phase, in which it was evaluated the efficacy of n-butyl-2-cyano-acrylate as the only support or as an adjunct to the usual methods in intestinal synthesis. histological and angiographic examination of the surgical specimens demonstrated the tissue autotoxicity and the good adhesive effect of the tissue glue. Because of these characteristic, authors propose its employment to reinforce intestinal sutures performed with the usual methods in high risk condition.
