[The frequency of gout and other disorders of uric acid metabolism in Dalmatia in comparison with these disorders in Croatia].

According to the literature gout is more frequent in Dalmatia than in continental part of Croatia. Higher average values of uric acid in serum, prevalence of hyperuicaemia as well as uric nephrolithiasis are also seen more frequently in Dalmatia comparing to the continental Croatia. This is probably genetically determined and is connected with metabolic changes of uric acid. Relative isolation of population in Dalmatian where the part of immigrants from other regions since the war started was very small favoured these changes. In addition some exogenous factors contribute in clinical manifestation of uric acid metabolic disturbances. The most important among them are consumption of food rich in nucleoproteins and dehydration in summer period.