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The immediate effects of splenectomy, radiotherapy and intensive chemotherapy on the immune status of patients with malignant lymphoma.脾切除术、放射治疗和强化化疗对恶性淋巴瘤患者免疫状态的即时影响。
Clin Oncol. 1977 Jun;3(2):137-44.
6
Demonstration of the neutrophil granulocyte functional capacity in silicosis, using the NBT test.
Rom J Intern Med. 1995 Jan-Jun;33(1-2):73-6.
7
Changes in immune status in patients undergoing splenectomy for the staging of Hodgkin's disease.接受脾切除术以进行霍奇金淋巴瘤分期的患者免疫状态的变化。
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Phagocytic function and antibody-dependent cellular cytotoxicity of human neutrophils in the presence of N-formimidoyl thienamycin.在N-甲酰亚胺基硫霉素存在的情况下人中性粒细胞的吞噬功能和抗体依赖性细胞毒性
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引用本文的文献

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Increased luminol-enhanced chemiluminescence of blood monocytes and granulocytes in Hodgkin's disease.霍奇金病患者血液单核细胞和粒细胞中鲁米诺增强化学发光增加。
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4
Pattern of leukocyte counts in untreated Burkitt's lymphoma patients in Ibadan.伊巴丹未治疗的伯基特淋巴瘤患者的白细胞计数模式。
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5
Comparative study of the endotoxin-stimulated nitroblue tetrazolium test in disease and health.疾病与健康状态下内毒素刺激的硝基蓝四氮唑试验的比较研究。
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本文引用的文献

1
The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes.抗体与抗原混合物对多形核白细胞的趋化作用。
J Exp Med. 1962 Mar 1;115(3):453-66. doi: 10.1084/jem.115.3.453.
2
A method of studying leukocytic functions in vivo.一种在体内研究白细胞功能的方法。
Ann N Y Acad Sci. 1955 Mar 24;59(5):757-805. doi: 10.1111/j.1749-6632.1955.tb45983.x.
3
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.人多形核白细胞的体外杀菌能力:儿童慢性肉芽肿病中活性降低。
J Clin Invest. 1967 Apr;46(4):668-79. doi: 10.1172/JCI105568.
4
Reticuloendothelial system phagocytic function in patients with Hodgkin's disease.霍奇金病患者的网状内皮系统吞噬功能
J Clin Invest. 1967 May;46(5):855-62. doi: 10.1172/JCI105585.
5
14 C-glucose oxidation in whole blood: a clinical assay for phagocyte dysfunction.全血中14C-葡萄糖氧化:一种用于检测吞噬细胞功能障碍的临床检测方法。
Infect Immun. 1972 Mar;5(3):414-5. doi: 10.1128/iai.5.3.414-415.1972.
6
Nitroblue tetrazolium reduction. False positive and false negative results.硝基蓝四氮唑还原试验。假阳性和假阴性结果。
Blood. 1973 Jun;41(6):921-5.
7
Defective phagocytosis due to tuftsin deficiency in splenectomized subjects.脾切除患者因促吞噬肽缺乏导致吞噬作用缺陷。
Am J Dis Child. 1973 May;125(5):663-5. doi: 10.1001/archpedi.1973.04160050017004.
8
Infection and nitroblue-tetrazolium reduction by neutrophils. A diagnostic acid.中性粒细胞的感染与硝基蓝四氮唑还原反应。一种诊断性酸。
Lancet. 1968 Sep 7;2(7567):532-4. doi: 10.1016/s0140-6736(68)92406-9.
9
The nitroblue tetrazolium test in lymphoma.
Am J Clin Pathol. 1973 Aug;60(2):198-201. doi: 10.1093/ajcp/60.2.198.

中性粒细胞在淋巴网状系统恶性肿瘤中的功能

Neutrophil function in lymphoreticular malignancy.

作者信息

Hancock B W, Bruce L, Richmond J

出版信息

Br J Cancer. 1976 May;33(5):496-500. doi: 10.1038/bjc.1976.80.

DOI:10.1038/bjc.1976.80
PMID:776198
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2024962/
Abstract

Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of infections). Candicidal capacity alone was depressed in 7 patients but 4 of these showed depressed cell-mediated immunity to Candida antigen. Splenectomy, radiotherapy and chemotherapy did not alter phagocytic function.

摘要

通过硝基四氮唑蓝试验(NBT 试验)和体外微生物杀伤技术,对 62 例淋巴网状恶性肿瘤患者的中性粒细胞功能进行了评估。发现吞噬作用正常或增强,在播散性疾病患者(无感染)中增强最为明显。仅 7 例患者的杀念珠菌能力降低,但其中 4 例对念珠菌抗原有细胞介导免疫功能降低。脾切除术、放疗和化疗并未改变吞噬功能。