中性粒细胞在淋巴网状系统恶性肿瘤中的功能
Neutrophil function in lymphoreticular malignancy.
作者信息
Hancock B W, Bruce L, Richmond J
出版信息
Br J Cancer. 1976 May;33(5):496-500. doi: 10.1038/bjc.1976.80.
Abstract
Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of infections). Candicidal capacity alone was depressed in 7 patients but 4 of these showed depressed cell-mediated immunity to Candida antigen. Splenectomy, radiotherapy and chemotherapy did not alter phagocytic function.
摘要
通过硝基四氮唑蓝试验（NBT 试验）和体外微生物杀伤技术，对 62 例淋巴网状恶性肿瘤患者的中性粒细胞功能进行了评估。发现吞噬作用正常或增强，在播散性疾病患者（无感染）中增强最为明显。仅 7 例患者的杀念珠菌能力降低，但其中 4 例对念珠菌抗原有细胞介导免疫功能降低。脾切除术、放疗和化疗并未改变吞噬功能。
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