[几种啮齿动物造血与成骨之间的关系]

[The relationship between hemopoiesis and osteogenesis in several species of rodents].

作者信息

Starostin V I, Michurina T V, Sludskaia A I, Khrushchov N G

出版信息

Biull Eksp Biol Med. 1976 Feb;81(2):231-4.

Abstract

Differentiation of the bone marrow transplants of rats, guinea pigs and dwarf hamsters placed under renal capsule of irradiated mice was studied. Active osteogenesis occurred in the transplants of rats and guinea pigs; as to hemopoiesis-it was irregular in rats and was arrested in guinea pigs. On the contrary, in the transplants of dwarf hamsters an intensive hemopoiesis was maintained and osteogenic capacity of the stroma was poor. It is supposed that the bone tissue in some rodent species was not a prerequisite for normal maintenance of myeloid hemopoiesis, while in others-primary bone stroma formation was necessary for the subsequent functioning of hemopoietic tissue.

摘要

研究了置于受辐照小鼠肾被膜下的大鼠、豚鼠和矮仓鼠骨髓移植的分化情况。大鼠和豚鼠的移植组织中发生了活跃的骨生成；至于造血作用，大鼠的造血作用不规则，豚鼠的造血作用则停滞。相反，矮仓鼠的移植组织中维持着强烈的造血作用，且基质的成骨能力较差。据推测，某些啮齿动物物种的骨组织并非维持髓系造血正常的必要条件，而在其他物种中，原发性骨基质形成对于造血组织的后续功能是必要的。