Molin S
Department of Microbiology, Technical University of Denmark, Lyngby.
Curr Opin Biotechnol. 1993 Jun;4(3):299-305. doi: 10.1016/0958-1669(93)90099-i.
Environmental applications of genetically engineered microorganisms have caused concern among scientists, the authorities and the general public. Despite the many potential benefits offered by gene technology to agriculture, environment protection and the medical sector, only a few cases of released engineered bacteria have been permitted. In this review, the design of safer organisms for release purposes is discussed with specific emphasis on the use of suicide systems to limit the survival of bacteria in the environment.
基因工程微生物在环境中的应用引起了科学家、当局和公众的关注。尽管基因技术给农业、环境保护和医疗领域带来了诸多潜在益处，但只有少数几例经过改造的细菌被允许释放。在这篇综述中，讨论了为释放目的设计更安全生物体的问题，特别强调了使用自杀系统来限制细菌在环境中的存活。
