来自中国蘑菇凤尾菇或鲍鱼菇（糙皮侧耳）的含抗肿瘤蛋白多糖
Antitumor protein-containing polysaccharides from a Chinese mushroom Fengweigu or Houbitake, Pleurotus sajor-caju (Fr.) Sings.
作者信息
Zhuang C, Mizuno T, Shimada A, Ito H, Suzuki C, Mayuzumi Y, Okamoto H, Ma Y, Li J
机构信息
Faculty of Agriculture, Shizuoka University Ohya, Japan.
出版信息
Biosci Biotechnol Biochem. 1993 Jun;57(6):901-6. doi: 10.1271/bbb.57.901.
Protein-containing polysaccharides extracted from fruiting bodies of a Chinese fungus named Feng Wei Gu, were fractionated and purified, and their antitumor activities were tested, out of which the following active fractions were obtained. FIo-a: A protein-containing xyloglucan, MW 280,000, polysaccharide: protein = 76:24 (w/w), polysaccharide consisting of Man:Gal:Xyl:Glc = 2:12:42:42 (molar ratio). [alpha]D23 + 25.3 degrees. FA-2: A protein-containing mannogalactan, MW 120,000, polysaccharide: protein = 76:16 (w/w), consisting of Xyl:Man:Gal = 9:35:56 (molar ratio), [alpha]D23 + 98.5 degrees. FII-1: A Protein-containing xylan (62:21 w/w). MW 200,000, [alpha]D23 + 8.7 degrees. FIII-1a: A protein-containing glucoxylan (15:71 w/w), [alpha]D23 + 30.7 degrees, MW 90,000, consisting of Glc:Xyl = 40:44 (molar ratio). FIII-2a: A protein-containing xyloglucan, MW 70,000, polysaccharide:protein = 69:3 (w/w), polysaccharide consisting of Xyl:Glc = 36:62 (molar ratio). [alpha]D23 + 38.6 degrees.
从中国真菌凤尾菇子实体中提取的含蛋白质多糖进行了分级分离和纯化，并测试了它们的抗肿瘤活性，从中获得了以下活性级分。FIo-a：一种含蛋白质的木葡聚糖，分子量280,000，多糖：蛋白质 = 76:24（w/w），多糖由甘露糖：半乳糖：木糖：葡萄糖 = 2:12:42:42（摩尔比）组成。[α]D23 + 25.3度。FA-2：一种含蛋白质的甘露半乳聚糖，分子量120,000，多糖：蛋白质 = 76:16（w/w），由木糖：甘露糖：半乳糖 = 9:35:56（摩尔比）组成，[α]D23 + 98.5度。FII-1：一种含蛋白质的木聚糖（62:21 w/w）。分子量200,000，[α]D23 + 8.7度。FIII-1a：一种含蛋白质的葡糖木聚糖（15:71 w/w），[α]D23 + 30.7度，分子量90,000，由葡萄糖：木糖 = 40:44（摩尔比）组成。FIII-2a：一种含蛋白质的木葡聚糖，分子量70,000，多糖：蛋白质 = 69:3（w/w），多糖由木糖：葡萄糖 = 36:62（摩尔比）组成。[α]D23 + 38.6度。
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