使用核磁共振成像技术测量中空纤维生物反应器中哺乳动物细胞的生长和分布情况。
Measurements of the growth and distribution of mammalian cells in a hollow-fiber bioreactor using nuclear magnetic resonance imaging.
作者信息
Callies R, Jackson M E, Brindle K M
机构信息
Department of Biological Sciences, University of Manchester, UK.
出版信息
Biotechnology (N Y). 1994 Jan;12(1):75-8. doi: 10.1038/nbt0194-75.
PMID:7764329
Abstract
We have used diffusion-weighted 1H NMR micro-imaging and localized spectroscopy techniques to monitor the growth and distribution of mammalian cells in a hollow-fiber bioreactor. Non-invasive NMR measurements of this type should also allow investigation of metabolic heterogeneity and assist in future designs of hollow-fiber systems.
摘要
我们已使用扩散加权1H核磁共振显微成像和局部光谱技术来监测中空纤维生物反应器中哺乳动物细胞的生长和分布。这种非侵入性核磁共振测量也应能用于研究代谢异质性，并有助于未来中空纤维系统的设计。
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