黄芪属植物中的抗菌异黄酮

Antimicrobial isoflavans from Astragalus species.

作者信息

el-Sebakhy N A, Asaad A M, Abdallah R M, Toaima S M, Abdel-Kader M S, Stermitz F R

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Egypt.

出版信息

Phytochemistry. 1994 Aug;36(6):1387-9. doi: 10.1016/s0031-9422(00)89728-9.

DOI:10.1016/s0031-9422(00)89728-9

PMID:7765429

Abstract

Two new antimicrobial isoflavans, 1-[(3R)-7,8-dimethoxybenzopyranyl]-4- hydroxybenzoquinone (astragaluquinone) and (3S)-7,1'-dihydroxy-8,3'-dimethoxyisoflavan (8-methoxyvestitol), and the known 7-hydroxy-2',3',4'-trimethoxyisoflavan were isolated from roots of Astragalus alexandrinus and A. trigonus. The structures of the new isoflavans were established by spectroscopic methods.

摘要

从亚历山大黄芪和三角黄芪的根部分离出两种新的抗菌异黄酮，1-[(3R)-7,8-二甲氧基苯并吡喃基]-4-羟基苯醌（黄芪醌）和(3S)-7,1'-二羟基-8,3'-二甲氧基异黄酮（8-甲氧基巢菜酚），以及已知的7-羟基-2',3',4'-三甲氧基异黄酮。通过光谱方法确定了新异黄酮的结构。