Carter K C
Human Genome Sciences Inc, Rockville.
Curr Opin Biotechnol. 1994 Dec;5(6):579-84. doi: 10.1016/0958-1669(94)90078-7.
The organization of transcription, processing, and transport of pre-mRNA within the nucleus is a major unsolved problem in cell biology. Several recent studies have helped to define the localization of specific DNAs, RNAs, and proteins within the nucleus and have led to various models for higher level organization of pre-mRNA metabolism.
前体信使核糖核酸(pre-mRNA)在细胞核内的转录、加工和运输的组织方式是细胞生物学中一个主要的未解决问题。最近的几项研究有助于确定细胞核内特定DNA、RNA和蛋白质的定位,并产生了前体信使核糖核酸代谢更高层次组织的各种模型。