Diels L, Dong Q, van der Lelie D, Baeyens W, Mergeay M
Flemish Institute for Technological Research (VITO), Mol, Belgium.
J Ind Microbiol. 1995 Feb;14(2):142-53. doi: 10.1007/BF01569896.
The plasmid-borne czc operon ensures for resistance to Cd2+, Zn2+ and Co2+ ions through a tricomponent export pathway and is associated to various conjugative plasmids of A. eutrophus strains isolated from metal-contaminated industrial areas. The czc region of pMOL30 was reassessed especially for the segments located upstream and downstream the structural genes czc CBA. In cultures grown with high concentrations of heavy metals, czc-mediated efflux of cations is followed by a process of metal bioprecipitation. These observations led to the development of bioreactors designed for the removal of heavy metals from polluted effluents.
质粒携带的czc操纵子通过三组分输出途径确保对Cd2+、Zn2+和Co2+离子具有抗性，并与从金属污染工业区分离的真养产碱杆菌菌株的各种接合质粒相关。尤其对pMOL30的czc区域位于结构基因czc CBA上下游的片段进行了重新评估。在含有高浓度重金属的培养物中，czc介导的阳离子外排之后会发生金属生物沉淀过程。这些观察结果促使人们开发出用于从污染废水中去除重金属的生物反应器。
