一种用于正电子发射断层显像（PET）成像的自动化[15Q]H2O生产与注射系统。

An automated [15Q]H2O production and injection system for PET imaging.

作者信息

Palmer B M, Sajjad M, Rottenberg D A

机构信息

PET Imaging Service, VA Medical Center, Minneapolis, MN 55417, USA.

出版信息

Nucl Med Biol. 1995 Feb;22(2):241-9. doi: 10.1016/0969-8051(94)00085-x.

DOI:10.1016/0969-8051(94)00085-x

PMID:7767320

Abstract

A computer controlled [15O]H2O injection system has been designed for multiple bolus injections during PET cerebral blood flow studies. The system is housed in a lead safe, and radiation exposure to nearby personnel is low; we have measured rates of approx. 100 microSv/h (10 mR/h) during 2 min of [15O]H2O production and < 50 microSv/h (< 5 mR/h) after 3.7 GBq (100 mCi) has been produced. Reproducibility studies show that the injected activity varies with a coefficient of variation of 2-3%.

摘要

已设计出一种计算机控制的[15O]H2O注射系统，用于正电子发射断层扫描（PET）脑血流研究中的多次团注注射。该系统置于铅屏蔽箱内，对附近人员的辐射暴露量较低；我们测量到，在[15O]H2O生成的2分钟内，辐射率约为100微希沃特/小时（10毫伦琴/小时），生成3.7吉贝可（100毫居里）后，辐射率小于50微希沃特/小时（小于5毫伦琴/小时）。重复性研究表明，注射活度的变化系数为2%-3%。