Guasti L, Cattaneo R, Rinaldi O, Rossi M G, Bianchi L, Gaudio G, Grandi A M, Gorini G, Venco A
Cattedra di Medicina Interna, II Facoltà di Medicina e Chirurgia, Università degli Studi di Pavia, Sede Varese, Italy.
Hypertension. 1995 Jun;25(6):1301-5. doi: 10.1161/01.hyp.25.6.1301.
Although a hypertension-related hypalgesia has been described, the relation between pain perception and the 24-hour blood pressure trend is still unknown. The ambulatory blood pressure monitoring parameters and dental pain sensitivity were correlated in 67 male subjects. The pulpar test (graded increase of test current of 0 to 0.03 mA) was performed on three healthy teeth, and mean dental pain threshold (occurrence of pulp sensation) and pain tolerance (time when the subjects asked for the test to be stopped) were evaluated. Three groups of subjects with normal (n = 34), intermediate (n = 13), and high (n = 20) blood pressure values were identified according to ambulatory monitoring results. Pain threshold differed among the three groups (P < .02), being higher in the group with highest blood pressure. The groups of hypertensive subjects showed higher pain tolerance than the normotensive group (P < .02). Pain threshold was correlated with 24-hour, diurnal, and nocturnal blood pressure values. Pain tolerance was also related to 24-hour blood pressure and to diurnal and nocturnal diastolic and mean arterial pressure values. Systolic and diastolic blood pressure loads were significantly associated with pain threshold, and diastolic load was also associated with tolerance. The blood pressure variability (SD) did not relate to pain perception. The 24-hour arterial pressure was more closely associated with pain perception than the blood pressure values obtained before the pulpar test. A close correlation between pain perception and 24-hour ambulatory blood pressure was demonstrated.(ABSTRACT TRUNCATED AT 250 WORDS)
尽管已有关于高血压相关痛觉减退的描述,但疼痛感知与24小时血压趋势之间的关系仍不清楚。对67名男性受试者的动态血压监测参数和牙齿疼痛敏感性进行了相关性研究。在三颗健康牙齿上进行牙髓测试(测试电流从0到0.03 mA分级增加),并评估平均牙齿疼痛阈值(牙髓感觉出现时)和疼痛耐受性(受试者要求停止测试的时间)。根据动态监测结果,将受试者分为三组,血压正常组(n = 34)、血压中间组(n = 13)和血压高值组(n = 20)。三组之间的疼痛阈值存在差异(P <.02),血压最高组的疼痛阈值更高。高血压受试者组的疼痛耐受性高于血压正常组(P <.02)。疼痛阈值与24小时、日间和夜间血压值相关。疼痛耐受性也与24小时血压以及日间和夜间舒张压和平均动脉压值有关。收缩压和舒张压负荷与疼痛阈值显著相关,舒张压负荷也与疼痛耐受性相关。血压变异性(标准差)与疼痛感知无关。与牙髓测试前获得的血压值相比,24小时动脉压与疼痛感知的相关性更强。研究证实疼痛感知与24小时动态血压之间存在密切相关性。(摘要截选至250字)