粪肠球菌临床分离株中万古霉素和高水平庆大霉素耐药基因在同一质粒上的连锁关系。
Linkage of vancomycin and high-level gentamicin resistance genes on the same plasmid in a clinical isolate of Enterococcus faecalis.
作者信息
Woodford N, Jones B L, Baccus Z, Ludlam H A, Brown D F
机构信息
Antibiotic Reference Unit, Central Public Health Laboratory, London, UK.
出版信息
J Antimicrob Chemother. 1995 Jan;35(1):179-84. doi: 10.1093/jac/35.1.179.
PMID:7768767
Abstract
A transferable 55-MDa plasmid which encoded resistance to both vancomycin and high concentrations of gentamicin was identified in a clinical isolate of Enterococcus faecalis. The plasmid hybridized with probes for the vanB and aac6'aph2" resistance genes. This is the first report of linkage of glycopeptide and high-level aminoglycoside resistance genes in an Enterococcus sp.
摘要
在一株粪肠球菌临床分离株中鉴定出一个可转移的55-MDa质粒，该质粒编码对万古霉素和高浓度庆大霉素的抗性。该质粒与vanB和aac6'-aph2"抗性基因的探针杂交。这是首次关于肠球菌属中糖肽类和高水平氨基糖苷类抗性基因连锁的报道。
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