Bourne W M, Gebhardt B M, Sugar A, Meyer R F, Kaufman H E
Invest Ophthalmol. 1976 Jul;15(7):541-2.
Recent studies have suggested that the spleen may be essential for the "immunologic privilege" enjoyed by corneal grafts. We tested this hypothesis in rabbits by performing 38 exchange penetrating keratoplasties between 19 normal rabbits and 19 rabbits that had undergone splenectomy. No significant difference was found in the number of corneas rejected or the mean graft survival time between the normal and splenectomized rabbits.
最近的研究表明，脾脏对于角膜移植所享有的“免疫赦免”可能至关重要。我们通过在19只正常兔子和19只已接受脾切除术的兔子之间进行38次穿透性角膜移植术对这一假设进行了检验。正常兔子和脾切除兔子之间在排斥角膜的数量或平均移植存活时间上未发现显著差异。
