Nomdedéu J F, Nomdedéu J, Martino R, Bordes R, Portorreal R, Sureda A, Domingo-Albós A, Rutllant M, Soler J
Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
J Clin Gastroenterol. 1995 Mar;20(2):157-9. doi: 10.1097/00004836-199503000-00020.
We report a patient who had refractory Hodgkin's disease and who received an autologous bone marrow transplantation and 8 months later developed abdominal pain associated with acute colonic dilation. The course of the patient was rapidly fatal due to a lobar pneumonia. Autopsy revealed signs of disseminated herpesvirus infection with marked hemorrhagic infarction of celiac sympathetic ganglia. This finding supports the hypothesis that denervation caused by virus reactivation and secondary hemorrhage is a main mechanism of acute colonic pseudoobstruction.
我们报告了一名患有难治性霍奇金病的患者，该患者接受了自体骨髓移植，8个月后出现与急性结肠扩张相关的腹痛。由于大叶性肺炎，该患者的病程迅速致命。尸检显示有播散性疱疹病毒感染的迹象，腹腔交感神经节有明显的出血性梗死。这一发现支持了由病毒再激活和继发性出血引起的去神经支配是急性结肠假性梗阻的主要机制这一假说。
