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尼莫地平:一种用于治疗血管痉挛的药物疗法。

Nimodipine: a drug therapy for treatment of vasospasm.

作者信息

Counsell C, Gilbert M, Snively C

机构信息

Shands Hospital, University of Florida, Gainesville 32610, USA.

出版信息

J Neurosci Nurs. 1995 Feb;27(1):53-6. doi: 10.1097/01376517-199502000-00009.

DOI:10.1097/01376517-199502000-00009
PMID:7769330
Abstract

Cerebral vasospasm presents a challenge for the nursing staff. To date, no effective prevention methods have been identified. The key to decreasing the mortality rates is in discovering a method of preventing or reversing the arterial narrowing caused by vasospasm. The nurse needs to be aware of the theories of vasospasm and the rationale for treatment. Neurologic assessment skills are important for the nurse to detect minimal changes that may indicate vasospasm. Nurses who are informed will be able to provide optimal care to patients with cerebral vasospasm and provide the necessary support for family members. Drug therapy continues to be the first-line defense in treating vasospasm. Nimodipine is a very promising drug with demonstrated effectiveness to reduce the neurologic deficits caused by vasospasm. Further research on the treatment of vasospasm following SAH is currently in progress.

摘要

脑血管痉挛给护理人员带来了挑战。迄今为止,尚未确定有效的预防方法。降低死亡率的关键在于找到一种预防或逆转由血管痉挛引起的动脉狭窄的方法。护士需要了解血管痉挛的理论及治疗原理。神经学评估技能对于护士检测可能表明血管痉挛的细微变化很重要。知识渊博的护士能够为脑血管痉挛患者提供最佳护理,并为家庭成员提供必要的支持。药物治疗仍然是治疗血管痉挛的一线防御手段。尼莫地平是一种非常有前景的药物,已证明其在减少由血管痉挛引起的神经功能缺损方面有效。目前正在对蛛网膜下腔出血后血管痉挛的治疗进行进一步研究。

相似文献

1
Nimodipine: a drug therapy for treatment of vasospasm.尼莫地平:一种用于治疗血管痉挛的药物疗法。
J Neurosci Nurs. 1995 Feb;27(1):53-6. doi: 10.1097/01376517-199502000-00009.
2
Nimodipine: the use of calcium antagonists to prevent vasospasm following subarachnoid hemorrhage.尼莫地平:使用钙拮抗剂预防蛛网膜下腔出血后的血管痉挛。
J Neurosci Nurs. 1990 Dec;22(6):382-4. doi: 10.1097/01376517-199012000-00009.
3
Prevention of symptomatic vasospasm after SAH by constant venous infusion of nimodipine.
Neurol Res. 1986 Dec;8(4):243-9. doi: 10.1080/01616412.1986.11739762.
4
Review of treatment of symptomatic cerebral vasospasm with nimodipine.尼莫地平治疗症状性脑血管痉挛的综述。
Acta Neurochir Suppl (Wien). 1988;45:51-5. doi: 10.1007/978-3-7091-9014-2_8.
5
[Management using nimodipine of cerebral vasospasm secondary to subarachnoid hemorrhage caused by rupture of an intracranial aneurysm].颅内动脉瘤破裂致蛛网膜下腔出血继发脑血管痉挛的尼莫地平治疗
Arch Invest Med (Mex). 1990 Apr-Jun;21(2):179-87.
6
Nimodipine evoked dilation of cerebral arteries early during the development of late vasospasm in subarachnoid hemorrhage.
Neurochirurgia (Stuttg). 1991 Sep;34(5):157-9. doi: 10.1055/s-2008-1052079.
7
New developments in the treatment of SAH-induced cerebral vasospasm.蛛网膜下腔出血所致脑血管痉挛治疗的新进展
Axone. 1993 Sep;15(1):25.
8
Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms.
Neurosurgery. 1988 Aug;23(2):154-7. doi: 10.1227/00006123-198808000-00004.
9
[Intravenous nimodipine in the treatment of cerebral vasospasm following subarachnoid hemorrhage caused by aneurysm rupture: a comparative multicenter study].
Agressologie. 1989 Jun;30(7):438-40.
10
Intracarotid slow bolus injection of nimodipine during angiography for treatment of cerebral vasospasm after SAH. A preliminary report.在血管造影期间经颈内动脉缓慢推注尼莫地平治疗蛛网膜下腔出血后脑血管痉挛:初步报告。
J Neurosurg. 1984 Aug;61(2):231-40. doi: 10.3171/jns.1984.61.2.0231.