Reusken C B, Neeleman L, Bol J F
Institute of Molecular Plant Sciences, Leiden University, The Netherlands.
J Virol. 1995 Jul;69(7):4552-5. doi: 10.1128/JVI.69.7.4552-4555.1995.
The coat protein (CP) of tobacco streak virus (TSV) can substitute for the early function of alfalfa mosaic virus (AIMV) CP in genome activation. Replacement of the CP gene in AIMV RNA 3 with the TSV CP gene and analysis of the replication of the chimeric RNA indicated that the TSV CP could not substitute for the function of AIMV CP in asymmetric plus-strand RNA accumulation but could encapsidate the chimeric RNA and permitted a low level of cell-to-cell transport.
烟草线条病毒(TSV)的外壳蛋白(CP)可替代苜蓿花叶病毒(AIMV)CP在基因组激活中的早期功能。用TSV CP基因替换AIMV RNA 3中的CP基因,并对嵌合RNA的复制进行分析,结果表明,TSV CP不能替代AIMV CP在不对称正链RNA积累中的功能,但可以将嵌合RNA包装起来,并允许其进行低水平的细胞间运输。