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[Ⅰ期间变型肾母细胞瘤的脊髓内转移]

[Intraspinal metastasis of stage I anaplastic Wilms tumor].

作者信息

Wiegel T, Grzyska U, Schwarz R, Escherich G

机构信息

Abteilung Strahlentherapie, Radiologischen Universitätsklinik, Hamburg-Eppendorf.

出版信息

Strahlenther Onkol. 1995 May;171(5):296-9.

PMID:7770786
Abstract

PURPOSE

Intraspinal metastasis of Wilms' tumors is a rare event with only 6 cases documented in the literature.

PATIENT AND METHODS

We report a case of an intraspinal metastasis by a young child with anaplastic Wilms' tumor (stage I). A 9-year-old girl developed 8 months following nephrectomy and pre-operative chemotherapy strong back pain. Within 2 weeks signs of beginning of spinal cord compression were obtained. The magnetic resonance imaging showed a spinal cord compression with an intraspinal tumor mass Th 8 to 10.

RESULTS

The child underwent immediate spinal cord decompression followed by chemotherapy and an additional radiotherapy of the metastatic region up to 30 Gy with most of neurologic recovery within 6 weeks.

CONCLUSIONS

The case illustrates the importance of rapidly responding neurologic complications in patients with Wilms' tumor, even in stage I.

摘要

目的

肾母细胞瘤的脊髓内转移是一种罕见事件,文献中仅记载了6例。

患者与方法

我们报告一例患有间变性肾母细胞瘤(I期)的幼儿发生脊髓内转移的病例。一名9岁女孩在肾切除术后及术前化疗8个月后出现严重背痛。在2周内出现了脊髓受压开始的体征。磁共振成像显示脊髓在胸8至胸10水平受到压迫,伴有脊髓内肿瘤肿块。

结果

该患儿立即接受了脊髓减压,随后进行化疗,并对转移区域追加了30 Gy的放疗,6周内大部分神经功能得以恢复。

结论

该病例说明了即使是I期肾母细胞瘤患者,对神经并发症迅速做出反应的重要性。

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