[Ⅰ期间变型肾母细胞瘤的脊髓内转移]
[Intraspinal metastasis of stage I anaplastic Wilms tumor].
作者信息
Wiegel T, Grzyska U, Schwarz R, Escherich G
机构信息
Abteilung Strahlentherapie, Radiologischen Universitätsklinik, Hamburg-Eppendorf.
出版信息
Strahlenther Onkol. 1995 May;171(5):296-9.
PURPOSE
Intraspinal metastasis of Wilms' tumors is a rare event with only 6 cases documented in the literature.
PATIENT AND METHODS
We report a case of an intraspinal metastasis by a young child with anaplastic Wilms' tumor (stage I). A 9-year-old girl developed 8 months following nephrectomy and pre-operative chemotherapy strong back pain. Within 2 weeks signs of beginning of spinal cord compression were obtained. The magnetic resonance imaging showed a spinal cord compression with an intraspinal tumor mass Th 8 to 10.
RESULTS
The child underwent immediate spinal cord decompression followed by chemotherapy and an additional radiotherapy of the metastatic region up to 30 Gy with most of neurologic recovery within 6 weeks.
CONCLUSIONS
The case illustrates the importance of rapidly responding neurologic complications in patients with Wilms' tumor, even in stage I.
目的
肾母细胞瘤的脊髓内转移是一种罕见事件，文献中仅记载了6例。
患者与方法
我们报告一例患有间变性肾母细胞瘤（I期）的幼儿发生脊髓内转移的病例。一名9岁女孩在肾切除术后及术前化疗8个月后出现严重背痛。在2周内出现了脊髓受压开始的体征。磁共振成像显示脊髓在胸8至胸10水平受到压迫，伴有脊髓内肿瘤肿块。
结果
该患儿立即接受了脊髓减压，随后进行化疗，并对转移区域追加了30 Gy的放疗，6周内大部分神经功能得以恢复。
结论
该病例说明了即使是I期肾母细胞瘤患者，对神经并发症迅速做出反应的重要性。
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