Sosroseno W, Herminajeng E
Department of Dental Public Health, Faculty of Dentistry, Gadjah Mada University, Yogyakarta, Indonesia.
FEMS Immunol Med Microbiol. 1995 Feb;10(3-4):171-80. doi: 10.1111/j.1574-695X.1995.tb00030.x.
Chronic inflammatory periodontal disease is known to be under the control of the immune response. However, the precise mechanism of the immunopathogenesis of this lesion has not yet been fully elucidated. In this review, the regulatory role of both lymphoid and non-lymphoid cells as well as cytokines and accessory molecules in the course of chronic inflammatory periodontal disease is discussed. Finally, based upon previous evidences, an attempt to establish a model of chronic inflammatory periodontal disease is made herein.
众所周知，慢性炎症性牙周病受免疫反应的调控。然而，该病变免疫发病机制的精确机制尚未完全阐明。在这篇综述中，将讨论淋巴细胞和非淋巴细胞以及细胞因子和辅助分子在慢性炎症性牙周病过程中的调节作用。最后，基于先前的证据，本文尝试建立慢性炎症性牙周病模型。
