Ikeda N, Handa Y, Khim S P, Durward C, Axéll T, Mizuno T, Fukano H, Kawai T
Second Department of Oral & Maxillofacial Surgery, School of Dentistry, Aichigakuin University, Nagoya, Japan.
Community Dent Oral Epidemiol. 1995 Feb;23(1):49-54. doi: 10.1111/j.1600-0528.1995.tb00197.x.
The aim of this study was to investigate the epidemiology of oral mucosal lesions in a selected Cambodian population to obtain pilot data useful in planning an oral health data base for the country. Due to unstable conditions in Cambodia, the validity of population data related to present census information is highly questionable. Therefore, prior to this investigation a census registration was carried out using local health workers as registrars in nine villages of a commune. In the period July 4-31, 1991, a total of 1319 individuals (953 women, 366 men, 15-99 yr) were examined by one oral surgeon in the nine villages of Kok Trop Commune, Kandal Stung District, southwest of the capital Phnom Penh. Clinical diagnoses were based on WHO criteria. Information on smoking habits, betel nut chewing habits, and alcohol use was collected by 4 Khmer dental personnel. In total, 71 lesions were recorded in 64 (4.9%) individuals. Leukoplakia was found in 1.1%, lichen lesions in 1.8%, candidosis in 1.4%, submucous fibrosis in 0.2%, cancer in 0.1% and other diagnoses in 0.8%. The prevalence of leukoplakia was 2.2% and 0.6% among men and women respectively, a statistically significant difference (P < 0.05). There were significantly more smokers (P < 0.01) among subjects with leukoplakia (64.3%) than among those without this lesion (28.6%). All subjects with lichen lesions were women. The age-adjusted relative risk for developing lichen among betel nut chewers as compared to non-chewers was 3.3.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是调查特定柬埔寨人群中的口腔黏膜病变流行病学情况，以获取有助于该国规划口腔健康数据库的初步数据。由于柬埔寨局势不稳定，与当前人口普查信息相关的人口数据的有效性极具疑问。因此，在本次调查之前，在一个公社的九个村庄以当地卫生工作者作为登记员进行了人口普查登记。1991年7月4日至31日期间，一名口腔外科医生在金边西南部干丹省斯登区阁德洛公社的九个村庄对总共1319人（953名女性、366名男性，年龄在15至99岁之间）进行了检查。临床诊断依据世界卫生组织标准。4名高棉牙科人员收集了吸烟习惯、嚼槟榔习惯和饮酒情况的信息。总共在64名（4.9%）个体中记录到71处病变。发现白斑的比例为1.1%，苔藓样病变为1.8%，念珠菌病为1.4%，口腔黏膜下纤维化0.2%，癌症0.1%，其他诊断为0.8%。男性和女性中白斑的患病率分别为2.2%和0.6%，差异有统计学意义（P<0.05）。有白斑病变的受试者中吸烟者明显更多（P<0.01）（64.3%），而无此病变者中吸烟者比例为28.6%。所有有苔藓样病变的受试者均为女性。与不嚼槟榔者相比，嚼槟榔者发生苔藓样病变的年龄调整相对风险为3.3。（摘要截短于250字）
