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马来西亚口腔黏膜病变的全国性流行病学调查。

A national epidemiological survey of oral mucosal lesions in Malaysia.

作者信息

Zain R B, Ikeda N, Razak I A, Axéll T, Majid Z A, Gupta P C, Yaacob M

机构信息

Dental Faculty, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Community Dent Oral Epidemiol. 1997 Oct;25(5):377-83. doi: 10.1111/j.1600-0528.1997.tb00959.x.

Abstract

The prevalence of oral mucosal lesions in Malaysia was determined by examining a representative sample of 11,707 subjects aged 25 years and above throughout the 14 states over a period of 5 months during 1993/1994. A two-stage stratified random sampling was undertaken. A predetermined number of enumeration blocks, the smallest population unit in the census publication, was selected from each state. With the selected enumeration block, a systematic sample of living quarters was chosen with a random start. The survey instrument included a questionnaire on sociodemographic characteristics and a clinical examination. The clinical examination was carried out by 16 specially trained dental public health officers and the diagnosis calibrated with a final concordance rate of 92%. The age in the sample ranged from 25 to 115 years with a mean of 44.5+/-14.0. The sample comprised 40.2% males and 59.8% females; 55.8% were Malays, 29.4% Chinese, 10.0% Indians and 1.2% other ethnic groups. Oral mucosal lesions were detected in 1131 (9.7%) subjects, 5 (0.04%) had oral cancer, 165 (1.4%) had lesions or conditions that may be precancerous (leukoplakia, erythroplakia, submucous fibrosis and lichen planus) and 187 (1.6%) had betel chewer's mucosa. The prevalence of oral precancer was highest amongst Indians (4.0%) and other Bumiputras (the indigenous people of Sabah and Sarawak) (2.5%) while the lowest prevalence was amongst the Chinese (0.5%).

摘要

1993年/1994年期间,在5个月内对马来西亚14个州的11707名25岁及以上的受试者进行了代表性抽样检查,以确定口腔黏膜病变的患病率。采用两阶段分层随机抽样。从每个州选择预定数量的普查街区(人口普查出版物中最小的人口单位)。在选定的普查街区中,以随机起点选择居住单元的系统样本。调查工具包括一份关于社会人口学特征的问卷和一次临床检查。临床检查由16名经过专门培训的牙科公共卫生官员进行,诊断校准后的最终一致性率为92%。样本年龄范围为25至115岁,平均年龄为44.5±14.0岁。样本中男性占40.2%,女性占59.8%;55.8%为马来人,29.4%为华人,10.0%为印度人,1.2%为其他种族。1131名(9.7%)受试者检测出口腔黏膜病变,5名(0.04%)患有口腔癌,165名(1.4%)患有可能为癌前病变(白斑、红斑、黏膜下纤维化和扁平苔藓)的病变或病症,187名(1.6%)患有嚼槟榔者黏膜病变。口腔癌前病变的患病率在印度人(4.0%)和其他原住民(沙巴和砂拉越的原住民)(2.5%)中最高,而在华人中患病率最低(0.5%)。

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