Hampson N B, Dunford R G, Kramer C C, Norkool D M
Hyperbaric Medicine Department, Virginia Mason Medical Center, Seattle, Washington 98111, USA.
J Emerg Med. 1995 Mar-Apr;13(2):227-31. doi: 10.1016/0736-4679(94)00144-8.
Medical directors of North American hyperbaric oxygen (HBO) facilities were surveyed to assess selection criteria applied for treatment of acute carbon monoxide (CO) poisoning within the hyperbaric medicine community. Responses were received from 85% of the 208 facilities in the United States and Canada. Among responders, 89 monoplace and 58 multiplace chamber facilities treat acute CO poisoning, managing a total of 2,636 patients in 1992. A significant majority of facilities treat CO-exposed patients with coma (98%), transient loss of consciousness (LOC) (77%), ischemic changes on electrocardiogram (91%), focal neurologic deficits (94%), or abnormal psychometric testing (91%), regardless of carboxyhemoglobin (COHb) level. Although 92% would use HBO for a patient presenting with headache, nausea, and COHb 40%, only 62% of facilities utilize a specified minimum COHb level as the sole criterion for HBO therapy of an asymptomatic patient. When COHb is used as an independent criterion to determine HBO treatment, the level utilized varies widely between institutions. Half of responding facilities place limits on the delay to treatment for patients with only transient LOC. Time limits are applied less often in cases with persistent neurologic deficits. While variability exists, majority opinions can be derived for many patient selection criteria regarding the use of HBO in acute CO poisoning.
对北美高压氧(HBO)设施的医学主任进行了调查,以评估高压氧医学领域中用于治疗急性一氧化碳(CO)中毒的选择标准。在美国和加拿大的208家设施中,有85%的设施回复了调查。在回复者中,89家单人舱和58家多人舱设施治疗急性CO中毒,1992年共治疗了2636名患者。绝大多数设施治疗CO中毒患者时,无论碳氧血红蛋白(COHb)水平如何,只要患者出现昏迷(98%)、短暂意识丧失(LOC)(77%)、心电图缺血性改变(91%)、局灶性神经功能缺损(94%)或心理测试异常(91%),都会进行治疗。虽然92%的设施会对出现头痛、恶心且COHb为40%的患者使用HBO治疗,但只有62%的设施将特定的最低COHb水平作为无症状患者HBO治疗的唯一标准。当将COHb用作确定HBO治疗的独立标准时,各机构使用的水平差异很大。一半的回复设施对仅短暂LOC的患者的治疗延迟设置了限制。对于持续性神经功能缺损的情况,时间限制的应用较少。虽然存在差异,但对于急性CO中毒使用HBO治疗的许多患者选择标准,可以得出多数意见。