生长激素对生长激素缺乏症儿童动脉粥样硬化风险的有益作用。
Beneficial effect of growth hormone on atherogenic risk in children with growth hormone deficiency.
作者信息
Kohno H, Ueyama N, Yanai S, Ukaji K, Honda S
机构信息
Department of Endocrinology and Metabolism, Fukuoka Children's Hospital, Japan.
出版信息
J Pediatr. 1995 Jun;126(6):953-5. doi: 10.1016/s0022-3476(95)70220-2.
PMID:7776105
Abstract
We studied changes in the atherogenic index (total cholesterol divided by high-density lipoprotein cholesterol) in 12 prepubertal boys with growth hormone (GH) deficiency during 9 months of GH treatment. High-density lipoprotein cholesterol level increased until 5 months without significant changes in total cholesterol level; thus GH therapy may be beneficial in reducing the atherogenic index in boys with GH deficiency.
摘要
我们研究了12名青春期前生长激素（GH）缺乏男孩在接受9个月GH治疗期间致动脉粥样硬化指数（总胆固醇除以高密度脂蛋白胆固醇）的变化。高密度脂蛋白胆固醇水平在5个月前升高，而总胆固醇水平无显著变化；因此，GH治疗可能有助于降低GH缺乏男孩的致动脉粥样硬化指数。
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