Schein O D, Steinberg E P, Cassard S D, Tielsch J M, Javitt J C, Sommer A
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ophthalmology. 1995 May;102(5):817-23. doi: 10.1016/s0161-6420(95)30952-9.
To identify preoperative patient characteristics associated with a lack of improvement on one or more measures 4 months after cataract surgery.
The authors collected preoperative and 4-month postoperative information on 552 patients undergoing first-eye cataract surgery from the practices of 72 ophthalmologists in three cities. The principal outcomes assessed were (1) Snellen visual acuity, (2) a cataract-related symptom score (possible range: 0, 0 of 6 symptoms present or bothersome, to 18, all 6 symptoms very bothersome), and (3) a measure of functional impairment in patients with cataract--the VF-14 score (possible range: 0, inability to perform any of the applicable activities, to 100, no difficulty performing any of the applicable activities). Multiple logistic regression was used to assess the association between preoperative patient characteristics and failure to improve on one or more outcome measures. Multiple linear regression was used to estimate the adjusted rate of lack of improvement in one or more outcome measures for one group of patients compared with another.
Although 91 patients (16.5%) failed to improve on one or more of the outcome measures assessed, only 2 (0.4%) failed to improve on all three measures. The 91 patients who did not improve on at least one measure were approximately one sixth as likely to be satisfied with their vision postoperatively as the 461 patients who improved on all three outcome measures. Preoperative age of 75 years of age or older, VF-14 score of 90 or higher, cataract symptom score of 3 or lower, and ocular comorbidity (glaucoma, diabetic retinopathy, or age-related macular degeneration) were associated independently with increased likelihood of not improving on one or more measure (odds ratio: 3.57, 2.10, 3.29, and 2.16, respectively). The mean adjusted rate of failure to improve on at least one of the outcome measures ranged from 20.5% to 26.5% for patients with these preoperative characteristics compared with 8.8% to 13.8% for those patients without them. The preoperative level of Snellen visual acuity was not associated with the likelihood of not improving on one or more of the outcomes assessed.
The authors conclude that specific preoperative characteristics (age, comorbidity, cataract symptom score, and VF-14 score) are independent predictors of patient outcome after cataract surgery.
确定白内障手术后4个月一项或多项指标未改善的术前患者特征。
作者收集了来自三个城市72位眼科医生诊所的552例接受第一眼白内障手术患者的术前及术后4个月的信息。评估的主要指标为:(1)斯内伦视力表视力;(2)白内障相关症状评分(可能范围:0,6项症状均未出现或不困扰为0分,至18分,6项症状均非常困扰为18分);(3)白内障患者功能障碍指标——VF-14评分(可能范围:0,无法进行任何适用活动为0分,至100分,进行任何适用活动均无困难为100分)。采用多因素逻辑回归分析评估术前患者特征与一项或多项指标未改善之间的关联。采用多因素线性回归分析估计一组患者与另一组患者相比,一项或多项指标未改善的校正率。
尽管91例患者(16.5%)一项或多项评估指标未改善,但仅2例(0.4%)三项指标均未改善。91例至少一项指标未改善的患者术后对视力满意的可能性约为三项指标均改善的461例患者的六分之一。术前年龄75岁及以上、VF-14评分90分及以上、白内障症状评分3分及以下以及眼部合并症(青光眼、糖尿病视网膜病变或年龄相关性黄斑变性)均与一项或多项指标未改善的可能性增加独立相关(比值比分别为:3.57、2.10、3.29和2.16)。具有这些术前特征的患者至少一项指标未改善的平均校正率为20.5%至26.5%,而无这些特征的患者为8.8%至13.8%。术前斯内伦视力表视力水平与一项或多项评估指标未改善的可能性无关。
作者得出结论,特定的术前特征(年龄、合并症、白内障症状评分和VF-14评分)是白内障手术后患者预后的独立预测因素。