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肺结核患者血液淋巴细胞及病理病灶的表型与功能分析

[Phenotypic and functional analysis of blood lymphocytes and pathological focus in patients with pulmonary tuberculosis].

作者信息

Kosmiadi G A, Abramova Z P, Gergert V Ia, Titiukhina M V

出版信息

Probl Tuberk. 1995(2):42-3.

PMID:7777464
Abstract

A subpopulation study of lymphocytes concentrating in cavernous, lymph node tissues and blood from patients with fibrous-cavernous tuberculosis of the lungs showed that in spite of high CD3+ and CD4+ cell levels in the cavern, the response of these cells to mitogens may be weaker than blood lymphocyte response. IL-2 production by cavern lymphocytes varied and was unrelated to proliferative response of these cells to M. tuberculosis antigens.

摘要

对肺部纤维空洞型肺结核患者的海绵状、淋巴结组织及血液中聚集的淋巴细胞进行的亚群研究表明,尽管空洞内CD3 +和CD4 +细胞水平较高,但这些细胞对丝裂原的反应可能比血液淋巴细胞反应弱。空洞淋巴细胞产生的白细胞介素-2各不相同,且与这些细胞对结核分枝杆菌抗原的增殖反应无关。

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