[Effects of diaminodiphenylsulfone and rifampicin on biorhythms of lymphocyte level in intact mice].

Administration of DDS and R alone as well as in combination to CBA mice was studied for effects on blood lymphocyte biorhythms. These drugs were found to affect circadian rhythms of lymphocyte number. The changes depended on the season and time of administration. Allowances for the above changes help correct asynchronism thus improving the response rate.