West J B
Department of Medicine 0623A, University of California San Diego, La Jolla 92093-0623, USA.
Respir Physiol. 1995 Feb;99(2):225-32. doi: 10.1016/0034-5687(94)00094-g.
Recently there has been increasing commercial activity at altitudes of 3500-6000 m. Examples include new mines in northern Chile at altitudes of about 4500 m. Because the workers come from sea level, intolerance of the high altitude is a major problem. This degree of hypoxia reduces work capacity, mental efficiency and sleep quality. One novel solution is to raise the PO2 of the room air by adding oxygen to the room ventilation. This is remarkably effective. For example, at altitudes of 4000-5000 m, increasing the O2 concentration by 1% (e.g. from 21 to 22%) reduces the equivalent altitude by about 300 m. Thus raising the O2 concentration by 5% at the new mines reduces the equivalent altitude to 3000 m which is easily tolerated. The introduction of oxygen concentrators (molecular sieve) which require only electrical power makes O2 enrichment feasible. The fire hazard is less than in air at sea level. Everybody now expects that the ventilation of a room will provide a comfortable temperature and humidity. Control of the oxygen concentration can be regarded as a further logical step in man's control of his environment.
最近,海拔3500 - 6000米处的商业活动日益增多。例如,智利北部海拔约4500米处有新矿。由于工人来自海平面地区,对高海拔不耐受是一个主要问题。这种程度的缺氧会降低工作能力、思维效率和睡眠质量。一种新颖的解决办法是通过在房间通风中添加氧气来提高室内空气的氧分压。这非常有效。例如,在海拔4000 - 5000米处,将氧气浓度提高1%(如从21%提高到22%)可使等效海拔降低约300米。因此,在新矿将氧气浓度提高5%可使等效海拔降至3000米,这很容易耐受。仅需电力的制氧机(分子筛)的引入使氧气富集成为可能。火灾危险比海平面的空气环境小。现在每个人都期望房间通风能提供舒适的温度和湿度。控制氧气浓度可被视为人类控制其环境的又一合理举措。