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类风湿因子与手腕腱鞘炎和肱骨外上髁炎中的 HLA 抗原

Rheumatoid factor and HLA antigens in wrist tenosynovitis and humeral epicondylitis.

作者信息

Malmivaara A, Viikari-Juntura E, Huuskonen M, Aho K, Kivi P, Koskimies S, Kuosma E, Kurppa K

机构信息

Finnish Institute of Occupational Health, Helsinki, Finland.

出版信息

Scand J Rheumatol. 1995;24(3):154-6. doi: 10.3109/03009749509099304.

DOI:10.3109/03009749509099304
PMID:7777826
Abstract

A matched case-referent study was undertaken to assess whether rheumatoid factor (RF) is associated with repeating tenosynovitis or peritendinitis and whether HLA-B27 predisposes to epicondylitis. The study subjects consisted of 25 workers in manually strenuous jobs with a history of at least two episodes of tenosynovitis or peritendinitis in the wrist or forearm, or humeral epicondylitis, and their matched referents. The latex agglutination test was positive in seven of the 23 cases with tenosynovitis and in one of the referents (p = 0.03). The corresponding figures for IgM-RF by enzyme immunoassay were ten and two, respectively (p = 0.008). HLA-B27 antigen was found in five of the 13 workers with epicondylitis and in one worker with no such history (p = 0.13). It is possible that RF-positive repeating tenosynovitis represents an incomplete form of rheumatoid disease.

摘要

开展了一项配对病例对照研究,以评估类风湿因子(RF)是否与复发性腱鞘炎或腱鞘炎相关,以及HLA - B27是否易患肱骨外上髁炎。研究对象包括25名从事体力繁重工作的工人,他们有手腕或前臂至少两次腱鞘炎或腱鞘炎发作史,或肱骨外上髁炎病史,以及与之匹配的对照者。在23例腱鞘炎病例中,有7例乳胶凝集试验呈阳性,对照者中有1例呈阳性(p = 0.03)。通过酶免疫测定法检测IgM - RF的相应数字分别为10例和2例(p = 0.008)。在13例肱骨外上髁炎工人中,有5例发现HLA - B27抗原,在1例无此类病史的工人中也发现了该抗原(p = 0.13)。RF阳性的复发性腱鞘炎可能代表类风湿病的一种不完全形式。

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