Creemers M C, Chang A, Franssen M J, Fiselier T J, van Riel P L
Dept rheumatology, University Hospital Nijmegen, The Netherlands.
Scand J Rheumatol. 1995;24(3):185-7. doi: 10.3109/03009749509099314.
Pseudoporphyria is a photo-induced blistering disorder with increased skin fragility, caused among others by nonsteroidal antiinflammatory drugs. Lesions heal with scarring and milia. Porphyrin screen studies are normal in this disease. Histology and immunofluorescence resembles porphyria cutanea tarda. In this report we describe a cluster of three cases of naproxen-induced pseudoporphyria, and review briefly previously reported cases induced by naproxen. The majority of reported cases involve children. Physicians should be aware of this reversible skin disorder.
假性卟啉症是一种光诱导的水疱性疾病，皮肤脆性增加，非甾体抗炎药等可引发该病。皮损愈合后会留疤并形成粟丘疹。该疾病的卟啉筛查结果正常。组织学和免疫荧光表现类似于迟发性皮肤卟啉症。在本报告中，我们描述了3例萘普生诱发的假性卟啉症病例，并简要回顾了此前报道的由萘普生诱发的病例。报告的大多数病例涉及儿童。医生应了解这种可逆性皮肤疾病。
