Vaneeva N P, Ianishevskaia M N, Aleksandrova T N, Ianshina N L
Zh Mikrobiol Epidemiol Immunobiol. 1995 Jan-Feb(1):59-61.
The comparative study of the activity of P. aeruginosa specific antitoxins in 134 lots of commercial preparations of human immunoglobulin in parallel mouse experiments on the neutralization of the lethal effect of exotoxin and in ELISA made it possible to establish a high degree of correlation between their results and the possibility of using immunochemical assays instead of biological tests in the large-scale production of anti-P. aeruginosa immunoglobulin.
在134批市售人免疫球蛋白制剂中，通过平行小鼠实验对外毒素致死效应的中和作用以及酶联免疫吸附测定（ELISA），对铜绿假单胞菌特异性抗毒素活性进行了比较研究，结果表明，两种方法的结果之间具有高度相关性，并且在大规模生产抗铜绿假单胞菌免疫球蛋白时，有可能使用免疫化学测定法替代生物学检测法。
