Ianishevskaia M N, Kuz'mina N S, Kutimova L R, Lents M N, Minakova L V
Zh Mikrobiol Epidemiol Immunobiol. 1983 Jun(6):100-3.
Some lots of commercial normal human immunoglobulin have been found to contain antibodies neutralizing the action of P. aeruginosa exotoxin. The content of antibodies in human immunoglobulin preparations correlates to a certain degree with their protective activity determined in the passive protection test in white mice. Certain lots of normal human immunoglobulin have been found to possess protective activity, but contain no specific antitoxins. The clinical testing of these immunoglobulin preparations used for treating patients with Pseudomonas infections has yielded promising results.
已发现一些批次的商业正常人免疫球蛋白含有中和铜绿假单胞菌外毒素作用的抗体。人免疫球蛋白制剂中的抗体含量与其在小白鼠被动保护试验中测定的保护活性在一定程度上相关。已发现某些批次的正常人免疫球蛋白具有保护活性，但不含特异性抗毒素。对这些用于治疗铜绿假单胞菌感染患者的免疫球蛋白制剂进行的临床试验已取得了令人鼓舞的结果。
