Puri B K, Singh I
Department of Psychiatry, Charing Cross and Westminster Medical School, London.
Br J Clin Pract. 1995 May-Jun;49(3):129-30.
Previous studies have found a summer peak in the birth of individuals with Down's syndrome but have not tended to examine them into adulthood. The aims of this study were to look for evidence of a seasonal effect in birth and to uncover any differences in adulthood between those born in different seasons. The casenotes of all adults with Down's syndrome from the catchment area of a hospital for people with learning disability were examined. A summer peak in births was confirmed. Only 6% of births took place during January and February compared with the 17% expected (P = 0.019); birth during these 2 months was associated with female sex (P = 0.047). There was a trend for those born in December to March not to develop epilepsy (P = 0.053).
先前的研究发现唐氏综合征患者的出生存在夏季高峰，但往往没有对他们成年后的情况进行研究。本研究的目的是寻找出生季节效应的证据，并揭示不同季节出生的人在成年后的差异。对一家为学习障碍者服务的医院服务区内所有成年唐氏综合征患者的病历进行了检查。确认了出生的夏季高峰。1月和2月的出生人数仅占6%，而预期为17%（P = 0.019）；这两个月出生与女性性别有关（P = 0.047）。12月至3月出生的人有不患癫痫的趋势（P = 0.053）。
